Latest article: |
|
|
Recent articles: |
|
EBV Target Capture using Fluidigm Long-Range Access Array with Next Generation Sequencing
13 Aug 2010: This technical poster describes how Fluidigm unique Access Array™ chip technology has been used by the Core Genotyping facility at the National Cancer Institute (Bethesda, MD) to successfully capture and sequence the entire Epstein Barr Virus (EBV) genome from 4 individual patient DNA samples in a single sequence capture run.
Fluidigm Corporation
|
Using the NanoDrop 3300 Fluorospectrometer for Cancer Research Applications
05 Jul 2010: The application note demonstrates the NanoDrop 3300 fluorospectrometer can play an integral role in relevant and diverse cancer research applications. This unique, ultra-small footprint instrument measures micro-volume samples and offers convenience with pre-configured methods for common fluorophores; but is also flexible enough to be able to customize user-created methods and handle a wide range of fluorophores.
Thermo Scientific Nanodrop Products
|
Expansion and Differentiation of H7 Human Embryonic Stem Cells in Chemically Defined Medium Using Corning® Synthemax™ Surface
21 Jun 2010: In this application note Corning Synthemax Surface is used to support long-term self-renewal and differentiation of H7 hESCs. Cells demonstrated a stable doubling time, high level of expression of hESC phenotypic markers (Oct4, SSEA4 and TRA-1-60) and normal karyotype. Corning Synthemax Surface also supported successful directed differentiation of H7 cells into functional cardiomyocytes, proving suitability of Corning Synthemax Surface for both expansion and differentiation of hESC culture.
Corning Life Sciences
|
Stem Cell-Derived Human Neurons in CNS Drug Discovery
07 Jun 2010: In this application note from Molecular Devices reproducible batches of human neurons are generated that will significantly improve and impact CNS drug discovery. The stem cell-derived neurons express all known markers typically associated with mature neurons and are functionally active. These neurons have been used in a recent screen to identify antagonists of a novel GPCR target implicated in schizophrenia.
Molecular Devices
|
High-Throughput Low-Volume DNA Quantification and Analysis
03 Jun 2010: This application note details the very high speed at which the Thermo Scientific Multiskan GO can perform full DNA quantification and spectral analysis on large numbers of low volume (5 - 10 µl) samples. With the Multiskan® GO, measurement of full DNA spectra between 220-380 nm from 96 samples can be performed in less than three minutes, providing a spectral measuring capacity of over 2,000 samples per hour.
Thermo Fisher Scientific
|
DNA Measurements using the TrayCell
17 May 2010: This application note demonstrates the TrayCell as a useful tool for measuring the absorbance of samples where there is limited sample available or the sample needs to be recovered after measurement without dilution. Concentration values obtained with the TrayCell are comparable to those obtained with standard 10mm path length cuvettes.
Jenway Ltd
|
Reducing PCR Reaction Times by Using Faster Ramp Rates, Modifying Programs and Changing the Reaction Mix
17 May 2010: In this application note the rapid ramp rate of the TC-PLUS was demonstrated. In the first experiment described above, there was little if any difference in yield or sensitivity between reactions run on the TC-PLUS and the slower TC-512.
Techne, part of Bibby Scientific
|
Non-Contact Acoustic Liquid Dispensing Systems: New Challenges in Automation and Implementation in the Work Flow
10 May 2010: Agilent Automation Solutions has published a technical poster that describes the integration of true non-contact acoustic liquid dispensing technology within an Agilent BioCel System enabling a new level of high throughput automation in a drug discovery environment. The poster describes the configuration of a fully automated compound management solution for screening and developmental assay plates.
Agilent Automation Solutions
|
Electroporation of Smooth Muscle Cells Using the Gene Pulser MXcell Electroporation System
06 May 2010: In this application note, Bio-Rad optimizes experimental conditions for transfection of several different smooth muscle cell (SMC) types using the Gene Pulser MXcell electroporation system. Electroporation parameters were optimized based on SMC viability and transfection efficiency. Different SMC types showed differential responses to varying voltage and capacitance. The system allows multiple cell types to be simultaneously tested in one single experiment.
Bio-Rad Laboratories, Inc.
|
